Steinbeis Transfer Center Nucleic Acids Design

• Prediction of inhibitory and non-inhibitory siRNA related to functional gene validation and active ingredient development
• Prediction of antisense oligodesoxyribonucleotides (asODN) related to gene validation and active ingredient development
• Prediction of antisense ribonucleic acids (asRNA) and antisense genes
• Individual in silico design of functional RNA etc. Improvement of gene expression based on optimized mRNA structures
• In the pipeline: selection of effective, selective hybridization probes for DNA microarrays

• Analysis
• Selection and design of functional RNA secondary structures (siRNA, antisense, mRNA)

Steinbeis Transfer Magazine

• Molecule design for genetic therapy (Transfer 3/2009)
  Computer-aided nucleic acid design for gene and cell therapy to treat type 2 Gaucher’s disease