Steinbeis Transfer Center Biopolymer Analysis and Biomedical Mass Spectrometry

• Applied research and development projects
  • Biopolymer mass spectrometry
  • Methods of protein structure analysis
  • Proteome analysis
  • High resolution separation techniques/mass spectrometry (HPLC/CE/LC-MS)
  • Secondary structures/conformations analysis
  • Tertiary structure analysis/protein interaction
  • Enzyme and immunoaffinity analysis
  • Microchip methods used in bio-analysis
• Synthesis and analysis
  • Primary structure analysis/micro-sequencing
  • Proteome analysis/structure modification  (phosphorylation/glycosylation/lipids)
  • Molecular identification structures/epitope mapping
  • Synthesis, characterization of polypeptides
  • Chemical modification, fluorescence/stable-isotopes marked peptides
• Consulting, expert reports, concepts/method development of biopolymer and proteome analysis
• Research courses/training and special seminars, workshops on methods of biopolymer analysis
  • Biopolymer mass spectrometry
  • Proteome analysis
  • Protein isolation, cleaning
• Equipment/instrumental methods:
  • Protein separation/isolation/cleaning methods (HPLC, FPLC, multi-dimensional electrophoresis)
  • Spectroscopic methods (IR, UV, ORD/CD)
  • Immunoaffinity analysis
  • Edman protein micro-sequencing
  • Fluorescence marking
  • Semi/fully automatic peptide synthesis equipment
  • Micro equipment, automatic devices, PC workstations, databases for proteome analysis
  • Molecular modeling/protein structure databases
  • Sector field and flight time mass spectrometry (Electrospray/MALDI/FAB)
  • HPLC MS/Tandem MS (Electrospray)
  • High resolution Fourier transform ICR mass spectrometry (Nano-electrospray/MALDI)

• Mass spectrometry techniques of biopolymer analysis
• Structural definition, supramolecular association of membrane proteins
• Synthesis and structural analysis of modified proteins
• Structure and interaction of target proteins of neurodegenerative disease (neuroproteome analysis)
• Autoantigens/identification of structures in autoimmune diseases

Steinbeis Transfer Magazine

• An Impressive Treatment: Enzyme Therapy (Transfer 2/2018)
  Steinbeis experts conduct research into diagnostic and treatment processes for lysosomal storage diseases
• Editorial (Transfer 2/2018)
  
• New routes to biologically-inspired peptide active ingredients (Transfer 2/2013)
  Steinbeis team develops procedure to identify carbohydrate-specific lectin peptides at the molecular level
• Clinical diagnosis of lysosomal storage diseases (Transfer 2/2010)
  Steinbeis and partners analyze inborn errors of metabolism
• High-resolution proteome analytics (Transfer 2/2007)
  New methods in diagnosing and treating neuro-degenerative diseases

Yearbook Steinbeis Foundation´s Transfer Award – Löhn Award

• Clinical Diagnosis of Lysosomal Storage Diseases in Central and Eastern Europe (Löhn Award 2010)